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Brighton Townhouses / Martin Friedrich Architects

first_imgCopyAbout this officeMartin Friedrich ArchitectsOfficeFollowProductsSteelConcrete#TagsProjectsBuilt ProjectsSelected ProjectsResidential ArchitectureHousesBrightonAustraliaPublished on May 16, 2014Cite: “Brighton Townhouses / Martin Friedrich Architects” 16 May 2014. ArchDaily. Accessed 11 Jun 2021. ISSN 0719-8884Read commentsBrowse the CatalogMetal PanelsAurubisCopper Alloy: Nordic BrassCompositesMitrexPhotovoltaic Solar Cladding – BIPV CladdingPanels / Prefabricated AssembliesTechnowoodPanel Façade SystemArmchairsUniForArmchair – ParigiLouvers / ShuttersBruagShading Screens – Perforated Facade PanelsAluminium CompositesSculptformAluminium Façade BladesCultural / PatrimonialIsland Exterior FabricatorsSeptember 11th Memorial Museum Envelope SystemWire MeshJakobWebnet in a Gymnasium in GurmelsDoorsLinvisibileLinvisibile Pocket Door | MareaPaintKEIMMineral Paint for Concrete – KEIM Concretal®-WLouversReynaers AluminiumSolar ShadingHandlesFormaniFitting Collection – ARCMore products »Read commentsSave世界上最受欢迎的建筑网站现已推出你的母语版本!想浏览ArchDaily中国吗?是否翻译成中文现有为你所在地区特制的网站?想浏览ArchDaily中国吗?Take me there »✖You’ve started following your first account!Did you know?You’ll now receive updates based on what you follow! Personalize your stream and start following your favorite authors, offices and users.Go to my stream CopyHouses•Brighton, Australia Brighton Townhouses / Martin Friedrich Architects Australia ShareFacebookTwitterPinterestWhatsappMailOrhttps://www.archdaily.com/505835/brighton-townhouses-martin-friedrich-architects Clipboard Houses 1186 Pty Ltd Brighton Townhouses / Martin Friedrich ArchitectsSave this projectSaveBrighton Townhouses / Martin Friedrich Architects Manufacturers: Meizai, Signorino, S&A Stairs Eslec Vayco Structures Landscaping: Year:  Architects: Martin Friedrich Architects Area Area of this architecture project Area:  519 m² Year Completion year of this architecture project Electrical Contractor: “COPY” “COPY” Photographs Projects Buldier: Joinery:Touch Wood cabinetryMetal Work:Hiba Design & ConstructionTotal Site Area:697 sqm totalDesign Principal:Martin FriedrichProject Architects:Michael Ceckiewicz, Kris Treagus and Prashanth IyerCity:BrightonCountry:AustraliaMore SpecsLess SpecsSave this picture!© Derek SwalwellRecommended ProductsFiber Cements / CementsSwisspearlSwisspearl Largo Fiber Cement PanelsWoodTechnowoodPergola SystemsDoorsSky-FrameInsulated Sliding Doors – Sky-Frame ArcWindowsSolarluxSliding Window – CeroText description provided by the architects. In today’s world, while requiring their indoor areas to provide for a comfortable and perhaps luxurious lifestyle, many people no longer want or need the maintenance of large gardens.  These two townhouses in an affluent, Bayside suburb of Melbourne have been designed to be the perfect answer for this lifestyle.Save this picture!© Martin FriedrichThe minimalist, contemporary design of these Brighton townhouses include spacious living / dining rooms opening via sliding doors allowing full openings to entertainer’s courtyards with wrap around pools.Save this picture!Floor PlanThe main entry areas opens onto a fully glazed wall orientated to view the pool beyond. However the pivotal feature of this space is the free standing sculptural circular staircase transcending all three levels with a large circular skylight flooding the interior in natural light. Save this picture!© Derek SwalwellThe building is finished in a minimalist palette of pure white render externally with white louvers on the front and rear providing privacy from the neighbouring townhouse and breaking up the simple shapes of the cantilevered cuboidal forms.  Internally, the deep grey European oak flooring, Pietro Grigio marble and mink grey carpet contrast with the white walls and add warmth and richness. The colour of the flooring is repeated in custom designed cabinetry throughout the houses including the cinema and study. The pure white interior is further accentuated by the vivid colours of the artwork.Save this picture!Floor PlanOn the first floor 3 generous sized bedrooms enjoy access to private en-suites, walk in robes and private balconies. These are connected via a gallery walkway with a continuous skylight running along the entire length. This skylight is broken up into 8 glazed sections with gimbled lights in each section projecting on paintings below.Save this picture!© Martin FriedrichThe basement with natural light permeating from the skylight 3 level above houses cinema, cellar, gymnasium and a 5 car garage with turntable.Project gallerySee allShow lessTYIN tegnestue Releases Downloadable Guide to Design/Build in Underprivileged AreasArchitecture NewsAimé Patisserie / LUKSTUDIOSelected Projects Share Jack Merlo Design Save this picture!© Derek Swalwell+ 28 Share 2013 ArchDaily ShareFacebookTwitterPinterestWhatsappMailOrhttps://www.archdaily.com/505835/brighton-townhouses-martin-friedrich-architects Clipboard Structural Engineer: Photographs:  Derek Swalwell, Martin Friedrich, Gerard Warrener Manufacturers Brands with products used in this architecture project last_img read more

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Break the silence, buy radios for Burma

first_img Howard Lake | 25 June 2010 | News AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to LinkedInLinkedInShare to EmailEmailShare to WhatsAppWhatsAppShare to MessengerMessengerShare to MoreAddThis1 Tagged with: Digital Amnesty International UK’s second ‘crowdfunding’ campaign, launched in June 2010, asked supporters to donate to buy 4,000 radios to be distributed throughout Burma by the middle of July to help overcome censorship by enabling an estimated 50,000 people to access independent radio broadcasts.Amnesty specifically encouraged supporters to share the fundraising appeal using social media. “Ask your friends and family to get involved too. Share the campaign by email or on social networks”.http://blog.protectthehuman.com/break-the-silence-beat-the-junta-2/Amnesty launched its first ‘crowdfunding’ campaign in May to help fund its protest ad campaign against Shell; 2,014 people donated as a result.www.nma.co.uk/news/thousands-respond-to-amnesty-ad-funding-call-via-social-networks/3014901.article  87 total views,  3 views today  88 total views,  4 views today AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to LinkedInLinkedInShare to EmailEmailShare to WhatsAppWhatsAppShare to MessengerMessengerShare to MoreAddThis1 Advertisement Break the silence, buy radios for Burma About Howard Lake Howard Lake is a digital fundraising entrepreneur. Publisher of UK Fundraising, the world’s first web resource for professional fundraisers, since 1994. Trainer and consultant in digital fundraising. Founder of Fundraising Camp and co-founder of GoodJobs.org.uk. Researching massive growth in giving.last_img read more

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EPA’s Latest Atrazine Report Ignores Science

first_img Facebook Twitter EPA’s Latest Atrazine Report Ignores Science Facebook Twitter SHARE Previous articleMcDonald’s Announces New Antibiotics PolicyNext articleLieutenant Governor Debate will Focus on Ag Issues Hoosier Ag Today A recent Environmental Protection Agency draft report on atrazine does not take into account a large amount of scientific evidence that reaffirms the product is safe. The National Corn Growers Association’s Production and Stewardship Action Team says that sets a dangerous precedent. The team says federal law requires the EPA to make its decisions based on science, and the science is pretty clear. Atrazine is one of the safest and most effective crop management tools farmers have in their toolboxes. It is also one of the most studied products in history with 50 years of data available. EPA released its draft assessment in June.All pesticides must be registered with the EPA, and be re-registered every 15 years. When the EPA drafted the assessment, the agency ignored several high-quality studies that showed atrazine to be safe. Instead, the EPA used studies its own Science Advisory Panel called “flawed” back in 2012.Source: NAFB News Service Home News Feed EPA’s Latest Atrazine Report Ignores Science SHARE By Hoosier Ag Today – Aug 2, 2016 last_img read more

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Radio host forced to resign for interviewing exiled former premier

first_img ThailandAsia – Pacific Organisation September 15, 2009 – Updated on January 20, 2016 Radio host forced to resign for interviewing exiled former premier to go further Reporters Without Borders is today publishing Thai radio show host Jom Petpradab’s account of the harassment to which he was subjected after interviewing former Prime Minister Thaksin Shinawatra, who lives in exile in Dubai.As a result of the harassment that he and fellow employees at radio MCOT received the authorities, Job resigned from his job as host of the programme “Exclusive with Jom Petpradab” in order to protect his colleagues.After addressing several requests to Thaksin for an interview, Jom finally received a phone call from him from Dubai during his 6 September show proceeded to conduct the interview. Thaksin has been charged with corruption in Thailand and is regarded as a “fugitive” by the government.A veteran journalist, Jom has worked for more than 20 years for print media, radio and television.Here is his account: Red alert for green journalism – 10 environmental reporters killed in five years News Help by sharing this information May 12, 2021 Find out more News Follow the news on Thailand Covid-19 emergency laws spell disaster for press freedomcenter_img News RSF_en Jom Petpradab Statement From: Jom PetpradabRegarding: Thai media, freedom of speech, and freedom to information are under threat in Thailand by a government that is robbing the people of their rights and freedoms. My name is Jom Petpradab and I have been a working journalist in Thailand for more than 20 years in newspaper, radio, and television media. On Sunday morning, September 6th, 2009 while I was hosting my radio program, “Exclusive with Jom Petpradab”, I received a live call from former Prime Minister Thaksin Shinawatra who was in Dubai. He was interested in giving me an interview because the month previous I had contacted his personal lawyer requesting an interview. Before the interview started, I informed my audience that Thaksin was on the phone, that I was conducting the interview as an unbiased journalist. I reminded the audience that I am not a supporter of the former Prime Minister, was not interested in being used as an outlet for propaganda, and simply wanted my audience to be able to hear his opinion on the many accusations revolving around him. Ultimately, my motivation is to help my audience and the Thai nation better understand the political crisis that our country is embroiled in. Essentially, I was doing my job as a journalist. My interview with Thaksin lasted for 40 minutes and I conducted it ethically, without favoritism or prejudice, and exercised proper journalistic integrity. For example, I asked him why he does not resign from politics to help ease the political crisis, whether he is loyal or wants to harm the monarchy, why he doesn’t come back to Thailand to accept the criminal convictions against him, whether he smuggled funds from the country, and how he was funding his business and political interests while abroad. The interview, in Thai, can be found at the Prachatai (www.prachatai.com) website. A key question asked, and indeed a fundamental question for our country, is how we can negotiate our current political crisis and reconcile the conflict. While I am a journalist and have conducted my interview with proper journalistic ethics, I am still a citizen and hope that we can find a solution to political conflict without bloodshed. Thaksin, love him or hate him, is at the center of this crisis. He is not only a legitimate news maker but he is a central figure to the crisis and therefore his opinion on how to negotiate this conflict is essential. To this end, I asked Thaksin “The whole country, even red and yellow, wants peace, why don’t you call the Prime Minister or talk to the government to find a way to reconcile this conflict?” While I was conducting my interview with Thaksin, Sathit Wongnongpoey a Minister attached to the Prime Minister’s Office, called the president of MCOT radio to ask why he would allow Thaksin on a government radio station. He claimed Thaksin should not be allowed on government radio because his is a fugitive, has tried to attack the Privy Council, and has challenged the authority of the judicial system. He ordered the MCOT president to report to him within 24 hours to explain why MCOT was not following government policy for media not incite political unrest. Reporters at MCOT are now in fear of doing their jobs and feel that they must present favorable, unquestioning coverage of the government or face punishment. While press freedom, including government controlled media, is protected by Article 46 of the Thai constitution it is clear that the Thai media is unable to exercise its constitutionally guaranteed rights. In short, Thai media is not free and is subject to considerable governmental control. This is not simply a problem under the Premiership of Abhisit, but is part of a long history of restrictions on media freedom in Thailand. While Thaksin was Prime Minister he tried to intimidate the press through costly lawsuits or through direct ownership of media outlets. I had trouble with him while trying to interview his political opponents at the time. After the 2006 coup, the junta first threatened to have me fired for airing an interview with a taxi driver who was protesting the loss of democracy and I was finally fired after trying to air an interview with Thaksin immediately after the 2007 election. My difficulties trying exercise free and fair reporting are not unique but are representative of the whole profession which has suffered from a lack of freedom and persistent government interference. What has happened to me is simply an illustration of the lack of media freedom and trouble with government controlled media. Thai media, freedom of speech, and freedom to information are under threat in Thailand. The government is robbing the Thai people of their rights and freedoms and are prosecuting journalist who are trying to do their jobs. Since my interview, I have had to resign from my position at MCOT because the government has placed substantial pressure on my coworkers and I do not want them to continue to work in fear of government reprisal. Sincerely, ThailandAsia – Pacific Thai premier, UN rapporteurs asked to prevent journalists being returned to Myanmar August 21, 2020 Find out more News June 12, 2020 Find out more Receive email alertslast_img read more

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Journalists increasingly exposed to violence at protests in France

first_img June 4, 2021 Find out more Tension between reporters and demonstrators is escalating at the Sivens Dam protests. Fearing for his safety, freelance reporter Eric Bouvet had to flee an event organized on 2 November in honour of Rémi Fraisse, a demonstrator killed at the dam site on 26 October. Demonstrators were circulating a photo of Bouvet along with claims that he was a police infiltrator – a situation indicative of the level of tension and incomprehension between protesters and journalists. Journalists have been prevented from taking photos and doing live TV reports from Albi and Lisle-sur-Tarn, two towns near the dam project, and in particular from the so-called “ZAD” (Zone to Defend), where the dam’s opponents have established a camp. Two journalists with the newspaper La Voix du Nord were deliberately attacked during a demonstration 900 km to the north, in Lille, on 27 October in protest against Fraisse’s death. “As soon as our photographer pulled out his camera, demonstrators grabbed him and sprayed him with a pepper spray at close range, aiming at his eyes,” deputy editor Pierre Mauchamp told Reporters Without Borders, adding that the protesters were above all targeting photographers.Grégoire Souchay, a reporter with the Reporterre specialist news site who has been covering the opposition to the Sivens Dam, said protesters do not want to be photographed or filmed, and do not trust the media. The arrival of lots of reporters, including TV crews at the start of this month, after Fraisse’s death, exacerbated the tension, with demonstrators accusing the “mainstream media” of opposing the values they defend. Using websites and social networks, the demonstrators are trying to provide their own alternative coverage of their protests. This “self-coverage” phenomenon took off during last year’s protests against the proposed Notre-Dame-des-Landes airport near Nantes, when mainstream media reporters were insulted, sometimes attacked, and denied access to the protesters.During a roundtable organized by Reporters Without Borders in July of this year, Benjamin Girette of IP3 Press said: “Journalists are increasingly being told ‘you are manipulated, we get our information by other means.’ This kind of criticism is becoming systematic and fuels violent attitudes toward the media. You eventually get to the point where the most ‘institutional’ media, especially TV channels, can no longer cover protests.” Agence France-Presse photographer Jacques Demarthon said: “Journalists are increasingly being identified with the political class, above all because of the close links between the media and political parties. TV stations are automatically excluded, even before the demonstration starts. They are called the ‘corrupt media,’ the ‘evening news permanent lie’.”“Media coverage of demonstrations is an essential part of the way democracies function,” Reporters Without Borders secretary-general Christophe Deloire said. “It is natural that journalists do not just reflect the image that the protesters and police have of themselves. It is the media’s job to be independent observers. Physical and verbal violence against them is alarming and indicative of contempt for the principle of public debate.”Verbal and physical violenceThe violence has been even more serious during other protests. When the National Assembly was debating the gay marriage bill in April 2013, opponents protesting outside attacked two journalists with the LCP Assemblée Nationale TV channel and damaged their equipment. Anti-gay marriage demonstrators attacked two Rennes TV journalists a few days later in Rennes. And an AFP journalist was thrown to the grounds and repeatedly kicked during an anti-gay marriage demonstration in Paris on 26 May 2013. The aggressive rhetoric used by some of the protest organizers encouraged the violence. Shortly after the “Marriage for All” law was promulgated, the “French Spring” collective issued an “agenda (…) for immediate execution” that called for the “targeting” of media “organs” that “disseminate (gender) ideology.” The “Day of Anger” protest on 26 January 2014 saw more targeted attacks against journalists covering the demonstration, especially TV crews. A Canal Plus crew, in particular, was attacked by protesters shouting “journalists, collaborators.” Canal Plus anchor Yann Barthès said during his programme the next day that “Our journalists were attacked by people who kicked them, punched them and threw beverage cans at them.” There is so much hostility that some media sometimes provide their reporters with bodyguards. The iTélé news channel, for example, uses the services of a security company when it thinks its crews need protecting.Two journalists were attacked during a demonstration by Rouen and Le Havre port workers in Haute-Normandie on 12 February. A Chaîne Normande employee was hit while stowing equipment, while a demonstrator threatened a Paris-Normandie journalist and made him pose for photos taken by other demonstrators. After an hour covering a demonstration in defence of the threatened delivery of two Mistral warships to Russia in the western port city of Saint-Nazaire on 7 September, a Canal Plus crew was chased away by angry demonstrators. Members of the Breton region’s “Bonnets Rouges” anti-tax movement attacked iTélé reporter Baptiste Cordier during a live report from Quimper in November 2013.Journalists were also attacked during pro-Gaza and pro-Israeli demonstrations this past summer, especially in the Parisian suburb of Sarcelles on 19 July. Members of minority and radical groups, or isolated individuals, were responsible for most of these attacks. The Sarcelles victims included AFP photographer Jacques Demarthon, who could not work for three weeks after someone hit him in the back, breaking his shoulder, and Laurent Troude, a freelancer working for the newspaper Libération, who could not work for eight days after a demonstrator threw a cobblestone at his back. Someone grabbed France TV cameraman Benjamin Poulain’s camera while LTL News journalist Leopold Jimmy was hit by both pro-Gaza demonstrators and members of the Jewish Defence League (LDJ). Tension fuelled by the Israeli-Palestinian conflict led to other cases of violence. LDJ members beat Jonathan Moadab of the Ruptly news agency and smashed his equipment during a protest against anti-Semitism in the Paris district of Trocadéro on 19 March. Moadab was the target of a homemade bomb in September 2012, for which two LDJ members received jail sentences in June of this year. And police advised Courrier de l’Atlas reporter Nadir Dendoune not to cover a pro-Israeli demonstration “for her own safety.”Tension between police and journalistsAsked about the obligation to protect people during demonstrations, Olivier Pouchin, the head of the CRS riot police in the Paris area, said the police intervene when demonstrators attack journalists even if the police are not given specific training in this sort of action. He stressed the need for communication between reporters and the police. If journalists report their presence to the police at the start of a protest, it is easier for the police to protect them if violent clashes ensue, he said. Journalists sometimes hamper CRS operations, he said, especially when they are located between the police and demonstrators. Pouchin also insisted that, while some demonstrators may be suspicious of the media, the CRS is not opposed to being filmed by journalists, especially as media footage has sometimes enabled the CRS to demonstrate that allegations made them were unjustified.The police are sometimes themselves responsible for violence against journalists. Yves Monteil, a freelance photographer and co-founder of Citizen Nantes who has been covering the Notre-Dame-des-Landes protests since 2009, was struck by a flash-ball round fired by a CRS member on 22 February. The flash-ball round hit him as he was using a zoom lens and mini-camera to film the police using teargas on a group of journalists. Reporterre journalist Emmanuel Daniel was manhandled by police during a protest against the Sivens Dam project in Albi on 23 September but since then no serious police misconduct has been reported in the area. “Since the incident, the police have not prevented us from working,” said Reporterre founder and former Le Monde journalist Hervé Kempf. “I went there two weeks ago. I had to wait 20 minutes at a gendarme roadblock, but after that I did not run into any other problem.” Police obstructed Montpellier Journal reporter Lucie Lecherbonnier while she was covering the eviction of squatters in the southern city of Montpellier on 23 October. She told them several times she was a reporter despite not having her press card with her but a policeman nonetheless snatched the mobile phone she was using to film and photograph the eviction.RWB’s recommendationsIn the light of the above, Reporters Without Borders reiterates its recommendation regarding media coverage of demonstrations. In particular, RWB urges all participants in demonstrations:- To respect the freedom to film and photograph, given that participating in a demonstration necessarily entails the possibility of being filmed or photographed.- To not obstruct the work of journalists, to respect their physical integrity and to respect their equipment.- To respect the confidentiality of journalists’ sources.And RWB urges the French authorities:- To implement the recommendations of UN Human Rights Council Resolution 25/38, especially paragraphs 8, 10, 12 and 13.- To pay particular attention to the safety of journalists and the protection of freedom of information during demonstrations.- To recognize that the right to information is not contingent on possession of a press card or press accreditation.- To ensure that the police receive appropriate training. Instruction on media rights, on the right to film and photograph, and on civil liberties should be included in the curricula of police academies and police on-the-job training.- To prosecute anyone who obstructs the work of journalists (by seizing their equipment, by arresting them or in any other way) or anyone who attacks them while they are covering demonstrations. – To pass legislation that makes it an offence, with criminal penalties, for any public official to obstruct freedom of information.- To pass legislation protecting the confidentiality of journalists’ sources and prohibiting the seizure of their equipment.- To create a system for compensating journalists for medical expenses resulting from injuries or for confiscation or destruction of equipment. to go further RSF denounces Total’s retaliation against Le Monde for Myanmar story News Violence against journalists is becoming more and more common at all kinds of demonstrations in France, including the “Manif pour Tous” protests against same-sex marriage and the recent protests against the proposed Sivens Dam in the southern department of Tarn. Journalists have been telling Reporters Without Borders about the difficulties they increasingly encounter while trying to cover protests and the hostility to which they are exposed. Follow the news on France May 10, 2021 Find out more News RSF_en Receive email alerts FranceEurope – Central Asia News November 14, 2014 – Updated on January 20, 2016 Journalists increasingly exposed to violence at protests in France FranceEurope – Central Asia News June 2, 2021 Find out more Help by sharing this information Organisation “We’ll hold Ilham Aliyev personally responsible if anything happens to this blogger in France” RSF says Use the Digital Services Act to make democracy prevail over platform interests, RSF tells EUlast_img read more

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Tamer Mabrouk is the first blogger prosecuted by a company in Egypt

first_img Help by sharing this information News Detained woman journalist pressured by interrogator, harassed by prison staff Receive email alerts EgyptMiddle East – North Africa RSF_en Video (in Arabic)Tamer Mabroukenvoyé par rsf_internet. – L’actualité du moment en vidéo. Interview with Tamer Mabrouk- Why did the article on pollution give rise to so many problems?“Many important people such as the prefect of Port Said are fully aware of this company’s swindles and the pollution it causes. But they refuse to talk about it, probably as a result of pressure (…) Corruption is a major problem in Egypt and explains everything. Everything takes place in a flagrantly illegal fashion and the embezzlement of public funds is commonplace nowadays (…) A deal was recently reached between Trust Chemical Industries and the Egyptian government. One of the agreement’s key clauses was the creation of 2,500 jobs for Egyptian workers. This condition was never respected but officials did not do any check.- Your article was censored. What was the reaction to this story?“The authorities told me they could do nothing. They said the company was too powerful. They advised me to turn to the Egyptian courts. My attempts to do this were unsuccessful so I decided to post my article online. My work constituted an uncompromising condemnation of their methods, of the system of corruption, pollution, human rights violations and arbitrary dismissals that had become frequent within the company (…) I brought a lawsuit against the company myself, requesting its closure as a source of pollution. The court ruled that it was not competent to hear the case. At the same time, Trust Chemical Industries asked me to withdraw my suit in return for a sum of money. When I refused outright, they demanded that I issue a retraction or a correction that would have been tantamount to an apology on my part.” May 26, 2009 – Updated on January 20, 2016 Tamer Mabrouk is the first blogger prosecuted by a company in Egypt EgyptMiddle East – North Africa فرض غرامة من 6000 يورو على مدوّن لفضحه التلوث الصناعي —————————Reporters Without Borders is outraged by the size of the fine that a court in the northeastern city of Port Said imposed on blogger Tamer Mabrouk on appeal today as a result of a defamation lawsuit by a private company, Trust Chemical Co., over information about pollution that he posted online. The court ordered him to pay a fine of 45,000 Egyptian pounds (5,759 euros), more than 15 times the 340-euro fine he was given at the original trial on 20 January.“The behaviour of the judicial authorities is inacceptable,” Reporters Without Borders said. “Mabrouk’s appeal hearing was rushed through and his case was not examined. The fine that has been imposed is an insult to free expression. It is clearly designed to ruin him and to deter him from expressing his views or taking any position. We call for his conviction to be quashed.”No Trust Chemical Co. representative attended today’s hearing, at which the judge upheld Mabrouk’s conviction. His lawyer said: “Tamer Mabrouk was tried under criminal law although he committed no crime. This is a dangerous decision that sends a negative message about the future of free expression. We have decided to try to get the ruling quashed.”The company sued Mabrouk over a June 2008 entry in his blog (http://elhakika.blogspot.com) accusing it of dumping waste in Manzalah Lake and the Suez canal that could be hazardous to humans and animals. He is the first Egyptian blogger to be sued over a blog entry. Reporters Without Borders is outraged by the size of the fine that a court in the northeastern city of Port Said imposed on blogger Tamer Mabrouk on appeal today as a result of a defamation lawsuit by a private company, Trust Chemical Co., over information about pollution that he posted online. See his testimony (in Arabic). Less press freedom than ever in Egypt, 10 years after revolution to go further February 6, 2021 Find out more News January 22, 2021 Find out more News Organisation February 1, 2021 Find out more Follow the news on Egypt Al Jazeera journalist Mahmoud Hussein back home after four years in prison Newslast_img read more

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What the Statewide Drought Declaration Means to Pasadena

first_imgCOVER: Right What the Statewide Drought Declaration Means to Pasadena Published on Friday, January 17, 2014 | 5:04 pm 8 recommended0 commentsShareShareTweetSharePin it Gov. Jerry Brown officially declared that California is in a drought emergency, as the state experiences its driest year in recorded history. A recent survey of the snowpack in the Sierra Nevada Mountains found the state’s water reserves are at just 20% of normal levels. Although Los Angeles has had its lowest annual rainfall in 100 years, the water situation in Southern California is a bit better due to investments in water storage.Over the past 20 years, the Metropolitan Water District of Southern California (MWD) has spent more than $5 billion in storage and infrastructure improvements that the region will be calling on to sustain supplies during these extremely dry times.Pasadena Water and Power (PWP) imports 60% of its water from MWD. Despite the record dry conditions, MWD does not plan to impose imported water supply restrictions for its member public agencies this year, although continued conservation is extremely important. The primary reasons for avoiding immediate water restrictions are ongoing efforts to dramatically lower demand and significant investments in storage the agency has made in recent years to capture supplies in wet years. MWD and PWP urge the community to continue conserving water, throughout the year.For the last five years, Pasadena customers have reduced about 18% of water usage and PWP continues to encourage and empower residents and business owners to conserve this precious resource. PWP plans to continue a year-round public awareness campaign that empowers residents and business owners to conserve water and educates the public on the water supply challenges facing California. Beginning in February, PWP has various educational water workshops scheduled, including:• A Water Supply Update Event on February 26, 2014• Spring Planning Organic Edible Gardening Workshop on March 8, 2014• California Friendly Landscape Workshops on March 22, 2014 and June 21, 2014The City of Pasadena reminds the community of the following citywide water waste prohibitions:• No watering outdoors between 9 a.m. and 6 p.m. or during periods of rain;• No excessive water flow or runoff onto pavement, gutters or ditches from watering or irrigating;• No washing down paved surfaces unless for safety or sanitation, in which case a bucket, a hose with a shut-off nozzle must be used;• All property owners must fix leaks, breaks or malfunctions when they find them, or within seven days of receiving a notice from PWP;• Vehicles must be washed with a hand-held bucket and/or hose equipped with a water shut-off nozzle;• Restaurants may not serve drinking water unless by patron’s request;• Hotels and motels must give guests the option to decline daily bed linen and towel changes.PWP will continue monitor the California water supply situation and will update the City Council and community if tighter water use restrictions are required.For a complete list of water waste prohibitions please visit www.PWPweb.com/WaterWaste.For more information about Pasadena water, please visit www.PWPweb.com/savewater.For more information about the City of Pasadena visit www.cityofpasadena.net. Make a comment Top of the News HerbeautyInstall These Measures To Keep Your Household Safe From Covid19HerbeautyHerbeautyHerbeauty11 Yummy Spices For A Flat TummyHerbeautyHerbeautyHerbeautyThe Biggest Signs You Want To Be With Your Girlfriend ForeverHerbeautyHerbeautyHerbeautyNutritional Strategies To Ease AnxietyHerbeautyHerbeautyHerbeautyYou Can’t Go Past Our Healthy Quick RecipesHerbeautyHerbeautyHerbeautyNow She’s 19 – Look At Her Transformation! Incredible!HerbeautyHerbeauty Pasadena Will Allow Vaccinated People to Go Without Masks in Most Settings Starting on Tuesday Community News Community News Get our daily Pasadena newspaper in your email box. Free.Get all the latest Pasadena news, more than 10 fresh stories daily, 7 days a week at 7 a.m. Subscribecenter_img Business News Your email address will not be published. Required fields are marked * More Cool Stuff Pasadena’s ‘626 Day’ Aims to Celebrate City, Boost Local Economy EVENTS & ENTERTAINMENT | FOOD & DRINK | THE ARTS | REAL ESTATE | HOME & GARDEN | WELLNESS | SOCIAL SCENE | GETAWAYS | PARENTS & KIDS Name (required)  Mail (required) (not be published)  Website  faithfernandez More » ShareTweetShare on Google+Pin on PinterestSend with WhatsApp,Virtual Schools PasadenaHomes Solve Community/Gov/Pub SafetyPasadena Public WorksPasadena Water and PowerPASADENA EVENTS & ACTIVITIES CALENDARClick here for Movie Showtimes First Heatwave Expected Next Week Home of the Week: Unique Pasadena Home Located on Madeline Drive, Pasadenalast_img read more

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NASA Selects Five Mars Orbiter Concepts, JPL Will Manage the Studies

first_img Subscribe Top of the News Pasadena Will Allow Vaccinated People to Go Without Masks in Most Settings Starting on Tuesday Science and Technology NASA Selects Five Mars Orbiter Concepts, JPL Will Manage the Studies From STAFF REPORTS Published on Monday, July 18, 2016 | 11:52 am EVENTS & ENTERTAINMENT | FOOD & DRINK | THE ARTS | REAL ESTATE | HOME & GARDEN | WELLNESS | SOCIAL SCENE | GETAWAYS | PARENTS & KIDS faithfernandez More » ShareTweetShare on Google+Pin on PinterestSend with WhatsApp,Virtual Schools PasadenaHomes Solve Community/Gov/Pub SafetyCitizen Service CenterPASADENA EVENTS & ACTIVITIES CALENDARClick here for Movie Showtimes Community News Business News More Cool Stuff Your email address will not be published. Required fields are marked * Make a commentcenter_img Community News NASA’s Mars Exploration Program includes two active rovers and three active orbiters. Concept studies have begun for a potential future Mars orbiter mission. Image Credit: NASA/JPL/USGSNASA has selected five U.S. aerospace companies to conduct concept studies for a potential future Mars orbiter mission. Such a mission would continue key capabilities including telecommunications and global high-resolution imaging in support of the agency’s Journey to Mars.The companies contracted for these four-month studies are: The Boeing Company in Huntington Beach, California; Lockheed Martin Space Systems in Denver; Northrop Grumman Aerospace Systems in Redondo Beach, California; Orbital ATK in Dulles, Virginia; and Space Systems/Loral in Palo Alto, California.“We’re excited to continue planning for the next decade of Mars exploration,” said Geoffrey Yoder, acting associate administrator for NASA’s Science Mission Directorate in Washington.The concept studies will address how a potential new Mars orbiter mission could best provide communications, imaging and operational capabilities. They also will assess the possibilities for supporting additional scientific instruments and functionalities, in addition to optical communications. The orbiter concept under study would take advantage of U.S. industry’s technology capacities by using solar electric propulsion to provide flexible launch, mission and orbit capabilities.The Mars Exploration Program Analysis Group, an organization designed to provide input to NASA from the Mars research science community, published a report six months ago on recommended science objectives for a Mars orbiter. These studies will provide input for assessing the feasibility of addressing these objectives. NASA also is pursuing partnership interest in contributing to this potential mission.NASA’s Jet Propulsion Laboratory in Pasadena, is managing the concept studies under the direction of the agency’s Mars Exploration Program.NASA is on an ambitious Journey to Mars that includes sending humans to the Red Planet in the 2030s. The agency’s robotic spacecraft are leading the way, with two active rovers, three active orbiters, the planned launch of the InSight lander in 2018, and development of the Mars 2020 rover.For more information about NASA’s Journey to Mars, visit https://www.nasa.gov/journeytomars 0 commentsShareShareTweetSharePin it Get our daily Pasadena newspaper in your email box. Free.Get all the latest Pasadena news, more than 10 fresh stories daily, 7 days a week at 7 a.m. Name (required)  Mail (required) (not be published)  Website  First Heatwave Expected Next Week Herbeauty8 Easy Exotic Meals Anyone Can MakeHerbeautyHerbeautyHerbeautyStop Eating Read Meat (Before It’s Too Late)HerbeautyHerbeautyHerbeautyA Mental Health Chatbot Which Helps People With DepressionHerbeautyHerbeautyHerbeautyThe Real Truth About The Pain Caused By MicrobladingHerbeautyHerbeautyHerbeautyWhat’s Your Zodiac Flower Sign?HerbeautyHerbeautyHerbeautyInstall These Measures To Keep Your Household Safe From Covid19HerbeautyHerbeauty Pasadena’s ‘626 Day’ Aims to Celebrate City, Boost Local Economy Home of the Week: Unique Pasadena Home Located on Madeline Drive, Pasadenalast_img read more

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Positive Data from FIREFISH Study of Evrysdi™ (risdiplam) in Infants with Type 1 Spinal…

first_img SOUTH PLAINFIELD, N.J., Feb. 24, 2021 /PRNewswire/ — PTC Therapeutics, Inc. (NASDAQ: PTCT), today announced the publication of results from the dose finding Part 1 of the pivotal FIREFISH study evaluating Evrysdi™ (risdiplam) in infants with symptomatic type 1 spinal muscular atrophy (SMA) in The New England Journal of Medicine (NEJM). The Part 1 data showed that patients treated with Evrysdi at 12 months demonstrated significant improvement in survival and developmental milestones, including the ability to survive without permanent ventilation, and the ability to sit without support for at least five seconds. Data from the study also demonstrated increased levels of survival motor neuron (SMN) protein, which is critical for maintaining nerve and muscle function. “The positive data published in The New England Journal of Medicine reinforces the benefits of Evrysdi and substantiates over a decade of work building our splicing platform to develop treatments for patients with diseases of high unmet medical need, like SMA,” said Stuart W. Peltz, Ph.D., Chief Executive Officer, PTC Therapeutics. “We believe the platform has broad potential for a large number of target genes across many disease areas.” The table below depicts improvements across Part 1 FIREFISH study after 12 months of treatment*: Pharmacodynamic data show infants receiving the recommended dose of Evrysdi had a median 1.9-fold increase from baseline of SMN protein at 12 months of treatment, with blood SMN protein concentration reaching its highest median value of 5.87 ng/ml (n=17; range 2.84 to 8.76) at four weeks, and at 12 months the median value was 5.66 ng/ml (n=15; range 2.66 to 8.60). FIREFISH is an open-label, two-part, pivotal clinical trial designed to evaluate the safety, tolerability, efficacy, pharmacokinetics (PK) and pharmacodynamics (PD) in infants with type 1 SMA. Part 1 was a dose-escalation study with the primary objective of assessing the safety profile of risdiplam in infants and determining the dose for Part 2. The median duration of treatment was 14.8 months at the time of analysis. The median age at enrollment was 6.7 months and symptom onset between the ages of 28 days to 3 months. Evrysdi is designed to treat SMA by increasing and sustaining the production of the SMN protein. SMN protein is found throughout the body and is critical for maintaining healthy motor neurons and movement. Roche leads the clinical development of Evrysdi as part of a collaboration with the SMA Foundation and PTC Therapeutics. Evrysdi is marketed in the United States by Genentech, a member of the Roche Group. About Evrysdi™ (risdiplam) Evrysdi™ is a survival motor neuron 2 (SMN2)-directed RNA splicing modifier designed to treat SMA caused by mutations in chromosome 5q that lead to SMN protein deficiency. Evrysdi is designed to distribute evenly to all parts of the body, including throughout the central nervous system (CNS). Evrysdi is administered daily at home in liquid form by mouth or feeding tube. In August 2020, the U.S. Food and Drug Administration approved Evrysdi for the treatment of spinal muscular atrophy for adults and children 2 months and older. Evrysdi is marketed in the United States by Genentech, a member of the Roche Group. Evrysdi is also approved in seven countries and has been filed in more than 50 countries worldwide. Clinical Trial Safety Data The safety profile of Evrysdi was established across FIREFISH and SUNFISH pivotal trials. The most common adverse reactions in later-onset SMA (incidence of at least 10 percent of patients treated with Evrysdi™ and more frequently than control) were fever, diarrhea, and rash. The most common adverse reactions in infantile-onset SMA were similar to those observed in later-onset SMA patients. Additionally, the most common adverse reactions (incidence of at least 10 percent) were upper respiratory tract infection, pneumonia, constipation, and vomiting. About the Risdiplam Clinical Studies FIREFISH (NCT02913482) – An open-label, two-part pivotal clinical trial in infants with type 1 SMA. Part 1 was a dose-escalation study in 21 infants with the primary objective of assessing the safety profile of risdiplam in infants and determining the dose for Part 2. Part 2 is a pivotal, single-arm study of risdiplam in 41 infants with type 1 SMA treated for two years followed by an open-label extension. Enrollment for Part 2 was completed in November 2018. The primary objective of Part 2 was to assess efficacy as measured by the proportion of infants sitting without support after 12 months of treatment, as assessed in the Gross Motor Scale of the Bayley Scales of Infant and Toddler Development – Third Edition (BSID-III) (defined as sitting without support for five seconds). The study met its primary endpoint. SUNFISH (NCT02908685) – A two part, double-blind, placebo controlled pivotal study in people aged 2 to 25 years with types 2 or 3 SMA. Part 1 (n=51) determined the dose for the confirmatory Part 2. Part 2 (n=180) evaluated motor function using total score of Motor Function Measure 32 (MFM-32) at 12 months. MFM-32 is a validated scale used to evaluate fine and gross motor function in people with neurological disorders, including SMA. The study met its primary endpoint. In addition to FIREFISH and SUNFISH, Evrysdi™ is being evaluated in a broad range of people with SMA, including in: JEWELFISH (NCT03032172) – An open-label exploratory trial designed to assess the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) in people with SMA aged 6 months to 60 years who received other investigational or approved SMA therapies for at least 90 days prior to receiving Evrysdi™. The study has completed recruitment (n=174). RAINBOWFISH (NCT03779334) – An open-label, single-arm, multi-center study, investigating the efficacy, safety, pharmacokinetics, and pharmacodynamics of risdiplam in babies (~n=25), from birth to 6 weeks of age (at first dose), with genetically diagnosed SMA, who are not yet presenting with symptoms. The study is currently recruiting. About Spinal Muscular Atrophy (SMA) Spinal muscular atrophy (SMA) is a severe, progressive neuromuscular disease that can be fatal. It affects approximately one in 10,000 babies and left untreated is the leading genetic cause of infant mortality. SMA is caused by a mutation of the survival motor neuron 1 (SMN1) gene, which leads to a deficiency of SMN protein. This protein is found throughout the body and is essential to the function of nerves that control muscles and movement. Without it, nerve cells cannot function correctly, leading to muscle weakness over time. Depending on the type of SMA, an individual’s physical strength and their ability to walk, eat or breathe can be significantly diminished or lost. About PTC Therapeutics, Inc. PTC is a science-driven, global biopharmaceutical company focused on the discovery, development and commercialization of clinically differentiated medicines that provide benefits to patients with rare disorders. PTC’s ability to globally commercialize products is the foundation that drives investment in a robust and diversified pipeline of transformative medicines and our mission to provide access to best-in-class treatments for patients who have an unmet medical need. For More Information: Investors & Media: Jane Baj +1 (908) 912-9167 [email protected] Forward-Looking Statements: This press release contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. All statements contained in this release, other than statements of historic fact, are forward-looking statements, including statements regarding: the future expectations, plans and prospects for PTC; advancement of PTC’s joint collaboration program in SMA, including any potential regulatory submissions, commercialization or royalty or milestone payments; PTC’s strategy, future operations, future financial position, future revenues, projected costs; and the objectives of management. Other forward-looking statements may be identified by the words “guidance”, “plan,” “anticipate,” “believe,” “estimate,” “expect,” “intend,” “may,” “target,” “potential,” “will,” “would,” “could,” “should,” “continue,” and similar expressions. PTC’s actual results, performance or achievements could differ materially from those expressed or implied by forward-looking statements it makes as a result of a variety of risks and uncertainties, including those related to: the outcome of pricing, coverage and reimbursement negotiations with third party payors for PTC’s products or product candidates that PTC commercializes or may commercialize in the future; the enrollment, conduct, and results of ongoing studies under the SMA collaboration and events during, or as a result of, the studies that could delay or prevent further development under the program, including any potential regulatory submissions and potential commercialization with respect to Evrysdi; significant business effects, including the effects of industry, market, economic, political or regulatory conditions; changes in tax and other laws, regulations, rates and policies; the eligible patient base and commercial potential of PTC’s products and product candidates; PTC’s scientific approach and general development progress; and the factors discussed in the “Risk Factors” section of PTC’s most recent Quarterly Report on Form 10-Q and Annual Report on Form 10-K, as well as any updates to these risk factors filed from time to time in PTC’s other filings with the SEC. You are urged to carefully consider all such factors. As with any pharmaceutical under development, there are significant risks in the development, regulatory approval and commercialization of new products. There are no guarantees that any product will receive or maintain regulatory approval in any territory, or prove to be commercially successful, including Evrysdi. The forward-looking statements contained herein represent PTC’s views only as of the date of this press release and PTC does not undertake or plan to update or revise any such forward-looking statements to reflect actual results or changes in plans, prospects, assumptions, estimates or projections, or other circumstances occurring after the date of this press release except as required by law. View original content: http://www.prnewswire.com/news-releases/positive-data-from-firefish-study-of-evrysdi-risdiplam-in-infants-with-type-1-spinal-muscular-atrophy-published-in-the-new-england-journal-of-medicine-301235049.html SOURCE PTC Therapeutics, Inc. Twitter Facebook Local NewsBusiness TAGS  Pinterest By Digital AIM Web Support – April 6, 2021 Facebookcenter_img Twitter Pinterest WhatsApp WhatsApp Positive Data from FIREFISH Study of Evrysdi™ (risdiplam) in Infants with Type 1 Spinal Muscular Atrophy Published in The New England Journal of Medicine Previous articlePureTech Founded Entity Karuna Therapeutics Announces New England Journal of Medicine Publication of Data from EMERGENT-1 Phase 2 Trial Evaluating KarXT in SchizophreniaNext articleHealth Insurance Premiums Have Decreased in a Number of Countries, According to Pacific Prime’s Latest Report Digital AIM Web Supportlast_img read more

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Easing of further restrictions to begin tomorrow

first_img Important message for people attending LUH’s INR clinic Facebook News, Sport and Obituaries on Monday May 24th Twitter Previous articleDisappointment for Curtis and Portsmouth as they miss out on Play-OffsNext article19 dead sheep found dumped in South Donegal river News Highland Loganair’s new Derry – Liverpool air service takes off from CODA Google+ Pinterest AudioHomepage BannerNews The Taoiseach’s urging people to “keep their guard up” as the country reopens this week.From tomorrow people will be able to get their hair cut, with the return of personal services, places of worship will reopen, click and collect will resume and larger outdoor gatherings will be allowed.Micheál Martin says the potential for an increase in cases is there due to increased movement.The Taoiseach says individual behaviours will be important if it’s to be successful:Audio Playerhttps://www.highlandradio.com/wp-content/uploads/2021/05/restrictions.wav00:0000:0000:00Use Up/Down Arrow keys to increase or decrease volume. Easing of further restrictions to begin tomorrow By News Highland – May 9, 2021 center_img Twitter WhatsApp Nine til Noon Show – Listen back to Monday’s Programme Facebook DL Debate – 24/05/21 RELATED ARTICLESMORE FROM AUTHOR WhatsApp Arranmore progress and potential flagged as population grows Google+ Pinterestlast_img read more

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